Self-expandable metal stents for malignant colonic obstruction: data from a retrospective regional SIED-AIGO study

Dig Liver Dis. 2014 Mar;46(3):279-82. doi: 10.1016/j.dld.2013.11.001. Epub 2013 Dec 8.

Abstract

Background: Self-expandable metal stents are a non-surgical option for the treatment of symptomatic malignant colorectal obstruction as palliative treatment or as a bridge to surgery.

Aims: To report data from a regional study on self-expandable metal stent (SEMS) placement for malignant colorectal obstruction.

Methods: Two hundred and four patients (male 54.9%, mean age of 69.5 ± 14.2) were retrospectively evaluated and data on technical and clinical success, and complications, were analyzed.

Results: Technical and clinical success rates were 99% and 94.6% respectively, with 36.7% treated on an emergency basis and 63.3% electively. Palliative treatment was administered to 70.1%, and as a bridge to surgery for 29.9%. Complications were 17 neoplastic ingrowths, 10 stent migrations, and 4 perforations. Palliative treatment was associated with a higher risk of stent ingrowth (p=0.003), and chemotherapy with a lower risk of stent ingrowth (p=0.009).

Conclusion: This regional study, although it has certain limitations, confirms the positive role of self-expandable metal stents in the treatment of symptomatic malignant colorectal obstruction, and that chemotherapy decreases the risk of ingrowth.

Keywords: Endoscopic placement; Malignant colonic obstruction; Multicenter experience; Self-expandable metal stents.

MeSH terms

  • Abdominal Neoplasms / complications
  • Abdominal Neoplasms / pathology
  • Aged
  • Aged, 80 and over
  • Carcinoma / complications
  • Carcinoma / pathology
  • Colonic Diseases / etiology
  • Colonic Diseases / therapy*
  • Colonic Neoplasms / complications
  • Colonic Neoplasms / pathology*
  • Colonoscopy*
  • Female
  • Foreign-Body Migration
  • Humans
  • Intestinal Obstruction / etiology
  • Intestinal Obstruction / therapy*
  • Lymphoma / complications
  • Lymphoma / pathology
  • Male
  • Metals
  • Middle Aged
  • Neoplasm Invasiveness
  • Palliative Care
  • Peritoneal Neoplasms / complications
  • Peritoneal Neoplasms / pathology
  • Retrospective Studies
  • Stents*
  • Treatment Outcome

Substances

  • Metals