Cost analysis of an intravenous to subcutaneous epoetin α conversion

Am J Nephrol. 2013;38(6):496-500. doi: 10.1159/000357052. Epub 2013 Dec 11.

Abstract

Background/aims: A cost analysis of a conversion from intravenous (IV) to subcutaneous (SC) epoetin α in patients receiving chronic in-center hemodialysis (HD).

Methods: This retrospective analysis compared epoetin α drug costs during a 6-month period of IV usage (July to December 2010, period 1) to a 6-month period of SC usage (July to December 2011, period 2) in four large in-center HD units. Data were collected from quarterly counts of HD patients receiving epoetin α and monthly inventory billing records.

Results: 622 HD patients who received IV epoetin α (period 1) were compared to 609 HD patients who received SC epoetin α (period 2). A 12.6% decrease in dose was observed. The average weekly cost of epoetin α was USD 173.02 per patient during the IV period versus USD 151.20 per patient during the SC period. This equated to a yearly cost savings of USD 1,135 per patient with SC epoetin α.

Conclusion: The switch from IV to SC epoetin α was successfully implemented in all four centers and realized significant cost savings.

Publication types

  • Multicenter Study

MeSH terms

  • Administration, Intravenous / economics*
  • Epoetin Alfa
  • Erythropoietin / administration & dosage*
  • Erythropoietin / economics*
  • Health Care Costs
  • Hemoglobins / analysis
  • Humans
  • Injections, Subcutaneous / economics*
  • Manitoba
  • Recombinant Proteins / administration & dosage
  • Recombinant Proteins / economics
  • Renal Dialysis / instrumentation*
  • Retrospective Studies
  • Treatment Outcome

Substances

  • Hemoglobins
  • Recombinant Proteins
  • Erythropoietin
  • Epoetin Alfa