Immunoglobulin g4 non-related sclerosing disease with intracardiac mass mimicking mitral stenosis: case report

J Korean Med Sci. 2013 Dec;28(12):1830-4. doi: 10.3346/jkms.2013.28.12.1830. Epub 2013 Nov 26.

Abstract

The cardiovascular system may be one of the target organs of both immunoglobulin G4 related and non-related systemic multifocal fibrosclerosis. We present a case of IgG4 non-related systemic multifocal fibrosclerosis mimicking mitral stenosis on echocardiography. For a more detailed differential diagnosis, we used multimodal imaging techniques. After surgical biopsy around the abdominal aortic area in the retroperitoneum, histological examination revealed IgG4 non-related systemic multifocal fibrosclerosis. We describe the multimodal imaging used to diagnose IgG4 non-related systemic multifocal fibrosclerosis and a positive response to steroid treatment. There have been no previous case reports of IgG4 non-related systemic multifocal fibrosclerosis with intracardiac involvement. Here, we report a case of IgG4 non-related systemic multifocal fibrosclerosis mimicking mitral stenosis.

Keywords: Immunoglobulin G4 Non-Related Sclerosing Disease; Left Atrium Mass; Mitral Valve Stenosis; Periaortitis.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Aorta, Abdominal / pathology
  • Diagnosis, Differential
  • Echocardiography
  • Female
  • Humans
  • Immunoglobulin G / blood*
  • Immunoglobulin G / immunology
  • Magnetic Resonance Imaging
  • Mitral Valve Stenosis / diagnosis
  • Myocardium / pathology*
  • Peritoneum / surgery
  • Positron-Emission Tomography
  • Retroperitoneal Fibrosis / congenital*
  • Retroperitoneal Fibrosis / diagnosis
  • Retroperitoneal Fibrosis / diagnostic imaging
  • Retroperitoneal Fibrosis / drug therapy
  • Steroids / therapeutic use
  • Tomography, X-Ray Computed

Substances

  • Immunoglobulin G
  • Steroids

Supplementary concepts

  • Multifocal fibrosclerosis