Intermittent letrozole therapy for metastatic breast cancer: case reports and literature review

Clin Breast Cancer. 2014 Apr;14(2):e41-5. doi: 10.1016/j.clbc.2013.10.009. Epub 2013 Oct 25.
No abstract available

Keywords: Aromatase inhibitor; Discontinuous therapy; Disease resistance.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Aromatase Inhibitors / therapeutic use*
  • Breast Neoplasms / drug therapy*
  • Breast Neoplasms / metabolism
  • Breast Neoplasms / pathology
  • Clinical Trials, Phase II as Topic
  • Female
  • Humans
  • Letrozole
  • Multicenter Studies as Topic
  • Neoplasm Staging
  • Neoplasms, Hormone-Dependent / drug therapy*
  • Neoplasms, Hormone-Dependent / metabolism
  • Neoplasms, Hormone-Dependent / secondary
  • Nitriles / therapeutic use*
  • Prognosis
  • Receptors, Estrogen / metabolism
  • Review Literature as Topic
  • Triazoles / therapeutic use*

Substances

  • Aromatase Inhibitors
  • Nitriles
  • Receptors, Estrogen
  • Triazoles
  • Letrozole