Revisiting pneumonia and exposure status in infants born to HIV-infected mothers

Pediatr Infect Dis J. 2014 Jan;33(1):70-2. doi: 10.1097/INF.0b013e31829f0ade.

Abstract

HIV-exposed uninfected infants are an increasing population. Past analyses have often categorized these infants as uninfected leading to inaccurate conclusions. We present a HIV exposure, rather than infection, based reanalysis of treatment failure among children with pneumonia to show that failure odds among HIV-exposed uninfected infants are intermediate between their unexposed and infected counterparts. Additional prospective studies aimed at better understanding this population are needed.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Retroviral Agents / therapeutic use
  • Child, Preschool
  • Female
  • HIV Infections / drug therapy
  • HIV Infections / epidemiology*
  • Humans
  • Infant
  • Infectious Disease Transmission, Vertical
  • Kenya / epidemiology
  • Odds Ratio
  • Pneumonia / epidemiology*
  • Pneumonia / therapy
  • Pneumonia / virology*
  • Pregnancy
  • Pregnancy Complications, Infectious / drug therapy
  • Pregnancy Complications, Infectious / epidemiology*
  • Pregnancy Complications, Infectious / virology*
  • South Africa / epidemiology
  • Treatment Failure

Substances

  • Anti-Retroviral Agents