In systemic sclerosis patients, bosentan is safe and effective for digital ulcer prevention and it seems to attenuate the development of pulmonary arterial hypertension

Rheumatology (Oxford). 2014 Mar;53(3):570-1. doi: 10.1093/rheumatology/ket424. Epub 2013 Dec 18.

Authors

Antonella Romaniello¹, Giovanna Viola, Felice Salsano, Edoardo Rosato

Affiliation

¹ Sapienza Department of Clinical Medicine, Clinical Immunology Unit, University of Rome, Viale dell'Università 37, 00185 Rome, Italy. [email protected].

PMID: 24357809
DOI: 10.1093/rheumatology/ket424

No abstract available

Publication types

Letter

MeSH terms

Bosentan
Cardiovascular Agents / adverse effects
Cardiovascular Agents / therapeutic use*
Dose-Response Relationship, Drug
Familial Primary Pulmonary Hypertension
Fingers
Humans
Hypertension, Pulmonary / prevention & control*
Scleroderma, Systemic / drug therapy*
Skin Ulcer / prevention & control*
Sulfonamides / adverse effects
Sulfonamides / therapeutic use*
Treatment Outcome

Substances

Cardiovascular Agents
Sulfonamides
Bosentan