Cinacalcet ameliorates cardiac fibrosis in uremic hearts through suppression of endothelial-to-mesenchymal transition

Int J Cardiol. 2014 Feb 15;171(3):e65-9. doi: 10.1016/j.ijcard.2013.11.105. Epub 2013 Dec 7.
No abstract available

Keywords: Cardiac fibrosis; Cinacalcet; Endothelial-to-mesenchymal transition; Parathyroid hormone; Uremia.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cinacalcet
  • Epithelial-Mesenchymal Transition / drug effects*
  • Epithelial-Mesenchymal Transition / physiology*
  • Fibrosis
  • Heart Diseases / drug therapy*
  • Heart Diseases / pathology
  • Humans
  • Hyperparathyroidism / drug therapy
  • Hyperparathyroidism / pathology
  • Male
  • Naphthalenes / pharmacology
  • Naphthalenes / therapeutic use*
  • Rats
  • Rats, Wistar
  • Uremia / drug therapy*
  • Uremia / pathology

Substances

  • Naphthalenes
  • Cinacalcet