Abstract
The effect of different doses of endotoxin (Lipopolysaccharide B) on Granulocyte-Macrophage Colony Stimulating Activity (GM-CSA) in the sera of "Swiss" male mice was measured by granulocyte-macrophage "in vitro" colony formation. The highest GM-CSA was found to be present 3-4 hours after 200 micrograms of endotoxin intraperitoneal injection.
MeSH terms
-
Animals
-
Colony-Forming Units Assay
-
Dose-Response Relationship, Drug
-
Endotoxins / administration & dosage*
-
Escherichia coli*
-
Injections, Intraperitoneal
-
Interleukin-3 / analysis*
-
Lipopolysaccharides / administration & dosage*
-
Male
-
Mice
-
Mice, Inbred Strains
Substances
-
Endotoxins
-
Interleukin-3
-
Lipopolysaccharides
-
lipopolysaccharide B