Abstract
Intrapleural and anti-adhesive materials were investigated in murine models, but not in a large animal model before clinical application. Our results failed to show any anti-adhesion effect of collagen fleece and suggested the thoracic physiology in murine models would not translate into a large animal model.
MeSH terms
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Animals
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Aprotinin / administration & dosage*
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Dogs
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Drug Combinations
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Fibrinogen / administration & dosage*
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Hemostatics / administration & dosage*
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Mice
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Models, Animal
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Pleural Cavity*
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Thrombin / administration & dosage*
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Tissue Adhesions / prevention & control*
Substances
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Drug Combinations
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Hemostatics
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tachocomb
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Fibrinogen
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Aprotinin
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Thrombin