Comorbidity of obsessive-compulsive disorder and substance use disorder: a new heuristic

Hum Psychopharmacol. 2014 Jan;29(1):89-93. doi: 10.1002/hup.2373. Epub 2013 Nov 27.

Abstract

Obsessive-compulsive disorder (OCD) and substance use disorder share several aspects of phenomenology and may be underpinned by a common mechanism with compulsivity at the core. Despite this overlap, the two disorders show a variable pattern of comorbidity. Here, we review the current evidence for comorbidity across clinical and epidemiological studies, and propose a new heuristic for substance use comorbidity in OCD, based on a hypothetical threshold of OCD severity.

Keywords: Obsessive-compulsive disorder; comorbidity; compulsivity; substance use disorder.

MeSH terms

  • Diagnosis, Dual (Psychiatry)*
  • Humans
  • Obsessive-Compulsive Disorder / epidemiology*
  • Obsessive-Compulsive Disorder / physiopathology
  • Risk
  • Severity of Illness Index
  • Substance-Related Disorders / epidemiology*
  • Substance-Related Disorders / physiopathology