The effect of age on apparent diffusion coefficient values in normal spleen: a preliminary study

G Li; P Xu; X Pan; H Qin; Y Chen

doi:10.1016/j.crad.2013.11.017

The effect of age on apparent diffusion coefficient values in normal spleen: a preliminary study

Clin Radiol. 2014 Apr;69(4):e165-7. doi: 10.1016/j.crad.2013.11.017. Epub 2014 Jan 20.

Authors

G Li¹, P Xu¹, X Pan¹, H Qin¹, Y Chen²

Affiliations

¹ Department of Radiology, East Hospital, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
² Department of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China. Electronic address: [email protected].

PMID: 24457017
DOI: 10.1016/j.crad.2013.11.017

Abstract

Aim: To investigate and characterize the effect of age on apparent diffusion coefficient (ADC) values in normal spleen.

Materials and methods: A population of 127 patients (age range 10-79 years, mean age 44.4 years) without magnetic resonance imaging findings in abdominal scans, was selected over a 5-year period. The ADC values of the spleen were analysed in all ages, and dependency of ADC values on age was characterized using Spearman's correlation coefficient test.

Results: A reduction of ADC values with ageing was found in the spleen (r = -0.702, p < 0.001).

Conclusions: The ADC values of the spleen decline with age. This should be taken into consideration when disease is diagnosed.

MeSH terms

Adolescent
Adult
Age Factors
Aged
Aging / physiology*
Child
Diffusion Magnetic Resonance Imaging*
Female
Humans
Image Processing, Computer-Assisted*
Male
Middle Aged
Observer Variation
Reproducibility of Results
Retrospective Studies
Spleen / physiology*
Statistics, Nonparametric