Efficacy of endoscopic gastroduodenal stenting for gastric outlet obstruction due to unresectable advanced gastric cancer: a prospective multicenter study

J Surg Oncol. 2014 Mar;109(3):208-12. doi: 10.1002/jso.23486. Epub 2013 Nov 6.

Abstract

Background and objectives: Gastroduodenal stents for gastric outlet obstruction due to unresectable advanced gastric cancer are increasingly used; however, their effects have not been fully evaluated.

Methods: A multicenter prospective observational study was performed. Patients were eligible if they had stage IV gastric cancer with a gastric outlet obstruction scoring system (GOOSS) score of 0 (no oral intake) or 1 (liquids only). Self-expandable metallic stents were delivered endoscopically. The effects of stents were evaluated.

Results: Twenty patients were enrolled and 18 were eligible (15 men, three women; median age, 70 years). Stent placement was successfully performed in all patients, with no complications. After stenting, a GOOSS score of 2 (soft solids only) or 3 (low-residue or full diet) was achieved in 13 (72%) patients. An improvement in the GOOSS score by one or more points was obtained in 16 (94%) patients. The median duration of fasting and hospital stay was 3 (range, 0-9) days and 18 (6-168) days, respectively. Chemotherapy was performed after stenting in 13 (72%) patients.

Conclusions: Gastroduodenal stents are thought to be feasible, safe, and effective for gastric outlet obstruction due to unresectable advanced gastric cancer, with rapid clinical relief and a short hospital stay.

Keywords: gastric outlet obstruction; stent; stomach neoplasms.

Publication types

  • Multicenter Study
  • Observational Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Equipment Design
  • Female
  • Gastric Outlet Obstruction / etiology*
  • Gastric Outlet Obstruction / therapy*
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Nutritional Status*
  • Palliative Care / methods
  • Prospective Studies
  • Serum Albumin / metabolism
  • Stents*
  • Stomach Neoplasms / complications*
  • Stomach Neoplasms / drug therapy*
  • Stomach Neoplasms / pathology
  • Treatment Outcome

Substances

  • Serum Albumin