[Overall survival: is it an objective endpoint for assessing the quality of surgical treatment for colorectal cancer?]

Rozhl Chir. 2013 Dec;92(12):690-3.
[Article in Czech]

Abstract

The monitoring of the quality of surgical treatment is the basic condition for improving the results of medical care. There are various endpoints available to assess the quality of surgical care. Survival time traditionally represents the key parameter for patients with colorectal cancer. Overall survival should not, however, be the only standard accepted measure of surgical care quality. Disease free survival in the early stages, neoadjuvant or adjuvant settings has been validated as a better option. Progression free survival, alone or aggregated with the quality of life, provides a useful, more sensitive parameter for advanced or metastatic colorectal cancer. The selection of appropriate, valid end-points is the basic prerequisite for improving the quality of surgical care for patients with colorectal cancer.

Keywords: colorectal cancer - disease free survival - progression free survival - overall survival..

MeSH terms

  • Colorectal Neoplasms / mortality*
  • Colorectal Neoplasms / pathology
  • Colorectal Neoplasms / surgery*
  • Disease Progression
  • Disease-Free Survival
  • Endpoint Determination*
  • Humans
  • Neoadjuvant Therapy
  • Neoplasm Staging
  • Quality Assurance, Health Care*