Abstract
The analysis of MUTYH-associated polyposis cases of the EPIPOLIP cohort confirms the importance of including serrated polyps in the diagnostic work-up of patients with oligopolyposis, suggests a role for screening polyps for the somatic c.34G>T KRAS mutation, and allows the implementation of a genetic testing strategy based on population data.
©2014 AACR
Publication types
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Research Support, Non-U.S. Gov't
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Comment
MeSH terms
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Adenomatous Polyposis Coli / diagnosis*
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Adenomatous Polyposis Coli / genetics*
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Colonic Polyps / genetics*
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Colorectal Neoplasms / diagnosis*
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Colorectal Neoplasms / genetics*
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DNA Glycosylases / genetics*
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Female
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Humans
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Male
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Mutation*
Substances
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DNA Glycosylases
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mutY adenine glycosylase