Hemolytic uremic syndrome in a 65-Year-old male linked to a very unusual type of stx2e- and eae-harboring O51:H49 shiga toxin-producing Escherichia coli

J Clin Microbiol. 2014 Apr;52(4):1301-3. doi: 10.1128/JCM.03459-13. Epub 2014 Feb 5.

Abstract

We report on a 65-year-old male patient with a Shiga toxin-producing Escherichia coli O51:H49 gastrointestinal infection and sepsis associated with hemolytic uremic syndrome (HUS) with a fatal outcome. The strains isolated harbored stx2e and eae, a very unusual and new virulence profile for an HUS-associated enterohemorrhagic E. coli.

Publication types

  • Case Reports

MeSH terms

  • Adhesins, Bacterial / genetics*
  • Aged
  • Escherichia coli Infections / diagnosis*
  • Escherichia coli Infections / microbiology
  • Escherichia coli Infections / pathology
  • Escherichia coli Proteins / genetics*
  • Fatal Outcome
  • Gastroenteritis / complications
  • Gastroenteritis / diagnosis*
  • Gastroenteritis / microbiology
  • Gastroenteritis / pathology
  • Hemolytic-Uremic Syndrome / diagnosis*
  • Hemolytic-Uremic Syndrome / microbiology
  • Hemolytic-Uremic Syndrome / pathology
  • Humans
  • Male
  • Sepsis / complications
  • Sepsis / diagnosis*
  • Sepsis / microbiology
  • Sepsis / pathology
  • Serogroup
  • Shiga Toxin 2 / genetics*
  • Shiga-Toxigenic Escherichia coli / genetics
  • Shiga-Toxigenic Escherichia coli / isolation & purification*
  • Virulence Factors / genetics

Substances

  • Adhesins, Bacterial
  • Escherichia coli Proteins
  • Shiga Toxin 2
  • Virulence Factors
  • eaeA protein, E coli