Symptom predictability in gastroesophageal reflux disease and role of proton pump inhibitor test

David S Estores

doi:10.1016/j.gtc.2013.11.002

Symptom predictability in gastroesophageal reflux disease and role of proton pump inhibitor test

Gastroenterol Clin North Am. 2014 Mar;43(1):27-38. doi: 10.1016/j.gtc.2013.11.002. Epub 2013 Dec 27.

Author

David S Estores¹

Affiliation

¹ Division of Gastroenterology, Hepatology and Nutrition, University of Florida, PO BOX 100214, Gainesville, FL 32610-0214, USA. Electronic address: [email protected].

PMID: 24503357
DOI: 10.1016/j.gtc.2013.11.002

Abstract

There are problems with the definition, assessment, and measurement of gastroesophageal reflux disease (GERD). The Reflux Disease Questionnaire and the GERD questionnaire are patient-reported outcome (PRO) measures for use in a primary care setting, which are easy to use and are validated. There is no widely accepted definition of a proton pump inhibitor test and performance of the test in the clinical setting is not standardized. The use of the PRO measures in primary care with predetermined cutoff values may help to reduce the cost of diagnosing GERD and increasing rates of response for evaluated patients to acid suppression.

Keywords: Gastroesophageal reflux/symptoms/diagnosis/treatment; Heartburn; Proton pump inhibitor; Regurgitation.

Publication types

Review

MeSH terms

Gastroesophageal Reflux / diagnosis*
Humans
Proton Pump Inhibitors*
Sensitivity and Specificity
Severity of Illness Index
Surveys and Questionnaires

Substances

Proton Pump Inhibitors