In vivo confocal microscopy features of cutaneous leishmaniasis

Dermatology. 2014;228(2):121-4. doi: 10.1159/000357525. Epub 2014 Jan 31.

Abstract

Background: Cutaneous leishmaniasis is widely distributed, Spain being a hypoendemic region. Noninvasive bedside detection of the histopathologic response to the intracellular organism that allows rapid diagnosis and prompt therapy could be the ideal tool to manage a commonly self-healing lesion. Confocal microscopy is a technique which allows in vivo examination of the skin at cellular resolution.

Methods: We describe the in vivo confocal microscopic features of cutaneous leishmaniasis, finding a correlation with dermoscopy and histopathology.

Conclusions and relevance: This case illustrates the capability of confocal microscopy to characterize the cutaneous infection by Leishmania organisms and to perform a noninvasive diagnosis.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Female
  • Humans
  • Leishmania / parasitology*
  • Leishmaniasis, Cutaneous / diagnosis*
  • Leishmaniasis, Cutaneous / parasitology
  • Microscopy, Confocal* / methods
  • Predictive Value of Tests
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Spain