Early and long-term clinical outcomes of bilio-intestinal diversion in morbidly obese patients

Surg Today. 2014 Aug;44(8):1424-33. doi: 10.1007/s00595-014-0856-x. Epub 2014 Feb 12.

Abstract

Purpose: To evaluate the early and long-term postoperative results of malabsorptive surgery in morbidly obese patients.

Methods: Between 2000 and 2007, 102 morbidly obese patients were referred to the Department of Surgery "Pietro Valdoni", "Sapienza" University of Rome, Policlinico "Umberto I°", Rome, Italy for malabsorptive surgery. All patients underwent derivative biliodigestive surgery after they had been reviewed by a team of surgeons, physicians, dieticians, and psychologists.

Results: There were no intra-operative complications, but two patients suffered postoperative pulmonary embolisms, which resolved with medical treatment. The mean postoperative hospital stay was 7 days, with no early or late mortality. Maximum weight loss was reached 12-24 months after surgery, while the mean percentage excess weight loss at 3-5 years ranged from 45 to 64 %. Specific postoperative complications in the first 2 years after surgery were abdominal abscess (n = 2), gastroduodenal reflux (n = 4), and incisional hernia (n = 6). Diabetes resolved in 98 % of the diabetic patients within a few weeks after surgery and blood pressure normalised in 86.4 % of those who had had hypertension preoperatively. Obstructive sleep apnoea and obesity hypoventilation syndrome also improved significantly in 92 % of the patients.

Conclusions: Morbidly obese patients can undergo biliodigestive surgery safely with good long-term weight loss and quality of life expectancy.

MeSH terms

  • Adult
  • Bariatric Surgery / methods*
  • Diabetes Mellitus / etiology
  • Diabetes Mellitus / therapy
  • Female
  • Humans
  • Hypertension / etiology
  • Hypertension / therapy
  • Italy
  • Male
  • Middle Aged
  • Obesity Hypoventilation Syndrome / etiology
  • Obesity Hypoventilation Syndrome / therapy
  • Obesity, Morbid / complications
  • Obesity, Morbid / physiopathology
  • Obesity, Morbid / surgery*
  • Quality of Life
  • Safety
  • Sleep Apnea, Obstructive / etiology
  • Sleep Apnea, Obstructive / therapy
  • Time Factors
  • Treatment Outcome
  • Weight Loss
  • Young Adult