Disseminated infection with Mycobacterium tilburgii in a male immunocompromised patient

Sarah Temmerman; Linos Vandekerckhove; Erica Sermijn; Dirk Vogelaers; Geert Claeys; Mario Vaneechoutte; Piet Cools; Steven Callens

doi:10.1128/JCM.03148-13

Disseminated infection with Mycobacterium tilburgii in a male immunocompromised patient

J Clin Microbiol. 2014 May;52(5):1777-9. doi: 10.1128/JCM.03148-13. Epub 2014 Feb 12.

Authors

Sarah Temmerman¹, Linos Vandekerckhove, Erica Sermijn, Dirk Vogelaers, Geert Claeys, Mario Vaneechoutte, Piet Cools, Steven Callens

Affiliation

¹ Department of General Internal Medicine and Infectious Diseases, Ghent University Hospital, Ghent, Belgium.

Abstract

Mycobacterium tilburgii is a nonculturable nontuberculous mycobacterium identifiable only by molecular methods. We report a case of disseminated M. tilburgii infection illustrating the importance of 16S rRNA gene sequencing to determine the responsible mycobacterial pathogen and the difficulties in tailoring antimycobacterial treatment in the absence of a culturable organism.

Publication types

Case Reports

MeSH terms

Adult
Anti-Bacterial Agents / therapeutic use
Humans
Immunocompromised Host / drug effects*
Male
Molecular Sequence Data
Mycobacterium Infections, Nontuberculous / diagnosis*
Mycobacterium Infections, Nontuberculous / drug therapy
Mycobacterium Infections, Nontuberculous / microbiology*
Nontuberculous Mycobacteria / drug effects
Nontuberculous Mycobacteria / genetics*
RNA, Ribosomal, 16S / genetics

Substances

Anti-Bacterial Agents
RNA, Ribosomal, 16S

Associated data

GENBANK/KF724951