Classification of the etiologies of acute liver failure in Japan: A report by the Intractable Hepato-Biliary Diseases Study Group of Japan

Satoshi Mochida; Yasuhiro Takikawa; Nobuaki Nakayama; Makoto Oketani; Takafumi Naiki; Yoshiyuki Yamagishi; Keiichi Fujiwara; Takafumi Ichida; Hirohito Tsubouchi

doi:10.1111/hepr.12295

Classification of the etiologies of acute liver failure in Japan: A report by the Intractable Hepato-Biliary Diseases Study Group of Japan

Hepatol Res. 2014 Apr;44(4):365-7. doi: 10.1111/hepr.12295. Epub 2014 Feb 17.

Authors

Satoshi Mochida¹, Yasuhiro Takikawa², Nobuaki Nakayama¹, Makoto Oketani³, Takafumi Naiki⁴, Yoshiyuki Yamagishi⁵, Keiichi Fujiwara⁶, Takafumi Ichida⁷, Hirohito Tsubouchi⁸

Affiliations

¹ Department of Gastroenterology and Hepatology, Saitama Medical University, Moroyama-machi, Japan.
² Department of Gastroenterology and Hepatology, School of Medicine, Iwate Medical University, Morioka, Japan.
³ Department of Digestive and Life-Style Related Disease, Health Research Course, Human and Environmental Sciences, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
⁴ Department of Gastroenterology, Gifu University Graduate School of Medicine, Gifu, Japan.
⁵ Department of Internal Medicine, School of Medicine, Keio University, Japan, Shinano-machi.
⁶ Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan.
⁷ Department of Gastroenterology, Shizuoka Hospital, Juntendo University, Izunokuni, Japan.
⁸ Kagoshima City Hospital, Kagoshima, Japan.

PMID: 24528608
DOI: 10.1111/hepr.12295

Abstract

The Intractable Liver Diseases Study Group of Japan, supported by the Ministry of Health, Labor and Welfare, established novel diagnostic criteria for "acute liver failure" in 2011. In these criteria, patients without histological findings of hepatitis are included in the disease entity of "acute liver failure", as in Europe and the USA. In this report, classification criteria for the etiologies of "acute liver failure" in Japan are proposed.

Keywords: HBV; autoimmune hepatitis; drug-induced liver injury; fulminant hepatic failure; fulminant hepatitis.