Laparoscopic resection of hepatocellular carcinoma: when, why, and how? A single-center experience

J Laparoendosc Adv Surg Tech A. 2014 Apr;24(4):223-8. doi: 10.1089/lap.2013.0502. Epub 2014 Feb 25.

Abstract

Purpose: The aim of this study was to evaluate short- and intermediate-term results of laparoscopic liver resection in selected patients with hepatocellular carcinoma (HCC).

Patients and methods: Eighty-five patients with HCC were subjected to liver resection between February 2007 and January 2013. From these, 30 (35.2%) were subjected to laparoscopic liver resection and were retrospectively analyzed. Special emphasis was given to the indication criteria and to surgical results.

Results: There were 21 males and 9 females with a mean age of 57.4 years. Patients were subjected to 10 nonanatomic and 20 anatomic resections. Two patients were subjected to hand-assisted procedures (right posterior sectionectomies); all other patients were subjected to totally laparoscopic procedures. Conversion to open surgery was necessary in 4 patients (13.3%). Postoperative complications were observed in 12 patients (40%), and the mortality rate was 3.3%. Mean overall survival was 29.8 months, with 3-year overall and disease-free survival rates of 76% and 58%, respectively.

Conclusions: Laparoscopic treatment of selected patients with HCC is safe and feasible and can lead to good short- and intermediate-term results.

Publication types

  • Evaluation Study

MeSH terms

  • Adrenal Gland Neoplasms / secondary
  • Adrenal Gland Neoplasms / surgery
  • Adult
  • Aged
  • Carcinoma, Hepatocellular / mortality
  • Carcinoma, Hepatocellular / surgery*
  • Conversion to Open Surgery
  • Disease-Free Survival
  • Embolization, Therapeutic
  • Feasibility Studies
  • Female
  • Hepatectomy / methods*
  • Hepatectomy / standards
  • Humans
  • Laparoscopy / methods*
  • Laparoscopy / standards
  • Length of Stay
  • Liver Neoplasms / mortality
  • Liver Neoplasms / surgery*
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / secondary
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / therapy*
  • Palliative Care / methods
  • Patient Selection
  • Postoperative Complications
  • Practice Guidelines as Topic
  • Retrospective Studies
  • Survival Rate
  • Treatment Outcome