Characteristics of hypertension subtypes and treatment outcome among elderly Korean hypertensives

J Am Soc Hypertens. 2014 Apr;8(4):246-53. doi: 10.1016/j.jash.2014.01.004. Epub 2014 Jan 11.

Abstract

There are limited data about characteristics of hypertension subtypes in Asian hypertensive patients and their impacts on treatment of hypertension. This prospective, multi-center, observational study evaluated 2439 hypertensive patients. (≥60 years) Inadequately controlled and drug-naïve patients were categorized into three hypertension subtypes (isolated systolic hypertension [ISH], combined systolic/diastolic hypertension [SDH], and isolated diastolic hypertension [IDH]), and proportions of each hypertension subtype were evaluated. After 6-month strict treatments, we compared the characteristics of patients who did not achieve target BP with those who did. In overall population, ISH was the most common subtype (53.2%; 1297/2439). However, in drug-naïve patients, SDH was the predominant hypertension subtype (59.6%; 260/436). Notably, the proportion of ISH was substantially lower than previously known data. Predictors associated with failure of reaching target BP were old age (>70 years), hypertension awareness, and baseline systolic blood pressure (≥160 mm Hg) for total patients. In drug naïve patients, hypertension awareness, ISH, and microalbuminuria were associated with treatment failure. These findings might have an impact on the evaluations and antihypertensive treatments of elderly Korean patients.

Keywords: Elderly; hypertension awareness; isolated systolic hypertension.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Antihypertensive Agents / therapeutic use*
  • Comorbidity
  • Female
  • Follow-Up Studies
  • Humans
  • Hypertension / classification*
  • Hypertension / drug therapy*
  • Hypertension / epidemiology
  • Male
  • Prospective Studies
  • Republic of Korea / epidemiology
  • Treatment Outcome

Substances

  • Antihypertensive Agents