Rectal cancer in inflammatory bowel diseases: MR imaging findings

Abdom Imaging. 2014 Jun;39(3):443-51. doi: 10.1007/s00261-014-0103-3.

Abstract

Purpose: To retrospectively analyze the MR imaging features of rectal cancer in patients with inflammatory bowel diseases (IBD).

Materials and methods: The MR imaging examinations of 13 patients with IBD-related rectal cancer were retrospectively reviewed. MR imaging included T2-weighted, diffusion-weighted (DW), and gadolinium chelate-enhanced MR imaging. MR imaging findings were analyzed and compared with endoscopic and histopathological findings.

Results: Eight patients (8/13; 62%) had active IBD and five (5/13; 38%) had quiescent IBD on MR imaging. Two different tumor patterns were individualized including clearly visible soft-tissue mass (4/13; 31%) (Type 1 tumor) and marked circumferential rectal wall thickening (9/13; 69%) (Type 2 tumor). Twelve tumors (12/13; 92%) showed high signal intensity on T2-weighted MR images. All six tumors studied with DW-MR imaging (6/6; 100%) showed high signal on DW-MR imaging with restricted diffusion on apparent diffusion coefficient (ADC) map. On gadolinium chelate-enhanced MR imaging, heterogeneous enhancement was observed in one tumor (1/13; 8%), whereas 12 tumors (12/13; 92%) showed homogeneous enhancement. MR imaging showed pelvic fistula and intrapelvic abscess in association with four (4/13; 31%) and two tumors (2/13; 15%), respectively.

Conclusion: Our limited retrospective study demonstrates that rectal cancer in IBD patients can present as a circumferential wall thickening resembling inflammation and can occur in the absence of fistula or abscess. The use of T2-weighted and DW-MR imaging is recommended to improve rectal cancer detection in patients with long-standing IBD.

MeSH terms

  • Adult
  • Aged
  • Contrast Media
  • Diffusion Magnetic Resonance Imaging / methods*
  • Echo-Planar Imaging / methods
  • Female
  • Humans
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / methods
  • Imaging, Three-Dimensional / methods
  • Inflammatory Bowel Diseases / complications*
  • Inflammatory Bowel Diseases / pathology*
  • Male
  • Meglumine
  • Middle Aged
  • Organometallic Compounds
  • Rectal Neoplasms / complications*
  • Rectal Neoplasms / diagnosis*
  • Rectal Neoplasms / pathology
  • Rectum / pathology
  • Retrospective Studies
  • Sensitivity and Specificity

Substances

  • Contrast Media
  • Organometallic Compounds
  • Meglumine
  • gadoterate meglumine