Edaravone rescues the lung by inhibiting lipid peroxidation and pro-inflammatory cytokines in a rat model

Chin Med J (Engl). 2014;127(5):968-70.

Authors

Zhouyang Wu¹, Yu Ming², Zhao Zhang¹, Jing Wu¹, Zhilin Wu¹, Shanglong Yao³

Affiliations

¹ Department of Anesthesia and Critical Care, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
² College of Health Science and Nursing, Wuhan Polytechnic University, Wuhan, Hubei 430022, China.
³ Department of Anesthesia and Critical Care, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China. Email: [email protected].

PMID: 24571896

No abstract available

MeSH terms

Acute Lung Injury / drug therapy*
Acute Lung Injury / metabolism
Animals
Antipyrine / analogs & derivatives*
Antipyrine / therapeutic use
Cytokines / metabolism*
Edaravone
Free Radical Scavengers / metabolism
Lipid Peroxidation / drug effects*
Male
Rats
Rats, Sprague-Dawley

Substances

Cytokines
Free Radical Scavengers
Edaravone
Antipyrine