Pitfalls of gestational age reassignment in evaluation of low maternal serum alpha-fetoprotein levels

S G Albright; L H Lingley; J W Seeds; B Lincoln-Boyea

doi:10.1016/s0002-9378(88)80086-3

Pitfalls of gestational age reassignment in evaluation of low maternal serum alpha-fetoprotein levels

Am J Obstet Gynecol. 1988 Aug;159(2):369-70. doi: 10.1016/s0002-9378(88)80086-3.

Authors

S G Albright¹, L H Lingley, J W Seeds, B Lincoln-Boyea

Affiliation

¹ Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill.

PMID: 2457319
DOI: 10.1016/s0002-9378(88)80086-3

Abstract

Accurate interpretation of low maternal serum alpha-fetoprotein levels depends on confirmation of gestational age by ultrasound. However, revision of gestational age estimations based solely on sonographic fetal biometry may result in excluding the fetus with trisomy from further diagnostic study.

Publication types

Case Reports

MeSH terms

Adult
Chromosomes, Human, Pair 18
Down Syndrome / diagnosis
Female
Fetal Diseases / diagnosis*
Gestational Age*
Humans
Pregnancy
Trisomy*
alpha-Fetoproteins / analysis*

Substances

alpha-Fetoproteins