Myocardial bridging: contemporary understanding of pathophysiology with implications for diagnostic and therapeutic strategies

Michel T Corban; Olivia Y Hung; Parham Eshtehardi; Emad Rasoul-Arzrumly; Michael McDaniel; Girum Mekonnen; Lucas H Timmins; Jerre Lutz; Robert A Guyton; Habib Samady

doi:10.1016/j.jacc.2014.01.049

Myocardial bridging: contemporary understanding of pathophysiology with implications for diagnostic and therapeutic strategies

J Am Coll Cardiol. 2014 Jun 10;63(22):2346-2355. doi: 10.1016/j.jacc.2014.01.049. Epub 2014 Feb 26.

Affiliations

¹ Andreas Gruentzig Cardiovascular Center, Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA.
² Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA.
³ Division of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, GA.

^# Contributed equally.

Abstract

Patients with myocardial bridging are often asymptomatic, but this anomaly may be associated with exertional angina, acute coronary syndromes, cardiac arrhythmias, syncope, or even sudden cardiac death. This review presents our understanding of the pathophysiology of myocardial bridging and describes prevailing diagnostic modalities and therapeutic options for this challenging clinical entity.

Keywords: coronary wall shear stress; intracoronary Doppler velocity and pressure; intravascular imaging; myocardial bridge; myotomy; percutaneous coronary intervention.

Myocardial bridging: contemporary understanding of pathophysiology with implications for diagnostic and therapeutic strategies

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