DWARF3 participates in an SCF complex and associates with DWARF14 to suppress rice shoot branching

Plant Cell Physiol. 2014 Jun;55(6):1096-109. doi: 10.1093/pcp/pcu045. Epub 2014 Mar 9.

Abstract

Strigolactones (SLs) are a novel class of plant hormones that inhibit shoot branching. Currently, two proteins in rice are thought to play crucial roles in SL signal transduction. DWARF14 (D14), an α/β hydrolase, is responsible for SL perception, while DWARF3 (D3), an F-box protein with leucine-rich repeats, is essential for SL signal transduction. However, how these two proteins transmit SL signals to downstream factors remains unclear. Here, we characterized a high-tillering dwarf rice mutant, gsor300097, which is insensitive to GR24, a synthetic analog of SL. Mapping and sequencing analysis showed that gsor300097 is a novel allelic mutant of D3, in which a nonsense mutation truncates the protein from 720 to 527 amino acids. The D3 gene was strongly expressed in root, leaf, shoot base and panicle. Nuclear-localized F-box protein D3 played a role in the SCF complex by interacting with OSK1, OSK5 or OSK20 and OsCullin1. In addition, D3 associated with D14 in a GR24-dependent manner in vivo. Taken together, our findings suggested that D3 assembled into an SCF(D3) complex and associated with D14 to suppress rice shoot branching.

Keywords: GR24; High-tillering dwarf; SCF complex; Shoot branching; Strigolactones.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Cullin Proteins / genetics
  • Cullin Proteins / metabolism
  • F-Box Proteins / genetics
  • F-Box Proteins / metabolism
  • Gene Expression Regulation, Plant*
  • Genes, Reporter
  • Hydrolases / genetics
  • Hydrolases / metabolism
  • Lactones / metabolism*
  • Mutation
  • Oryza / genetics*
  • Oryza / growth & development
  • Oryza / physiology
  • Phenotype
  • Phylogeny
  • Plant Growth Regulators / metabolism*
  • Plant Leaves / genetics
  • Plant Leaves / growth & development
  • Plant Leaves / physiology
  • Plant Proteins / genetics*
  • Plant Proteins / metabolism
  • Plant Roots / genetics
  • Plant Roots / growth & development
  • Plant Roots / physiology
  • Plant Shoots / genetics
  • Plant Shoots / growth & development
  • Plant Shoots / physiology
  • Seedlings / genetics
  • Seedlings / growth & development
  • Seedlings / physiology
  • Signal Transduction*
  • Two-Hybrid System Techniques

Substances

  • Cullin 1
  • Cullin Proteins
  • F-Box Proteins
  • Lactones
  • Plant Growth Regulators
  • Plant Proteins
  • strigol
  • Hydrolases