Unusual ¹⁸F-FDG PET/CT finding of an oxyphil parathyroid adenoma in a patient with Hodgkin's Lymphoma

Rev Esp Med Nucl Imagen Mol. 2014 Nov-Dec;33(6):370-3. doi: 10.1016/j.remn.2014.01.002. Epub 2014 Mar 4.

Abstract

Malignancy-associated hypercalcemia is a complication of advanced tumours that is associated to a poor prognosis. Thorough evaluation to establish its cause is essential because some patients may actually have undiagnosed primary hyperparathyroidism. We report a case of a patient affected by Hodgkin's Lymphoma and persistent hypercalcemia with an incidental (18)F-FDG PET/CT finding in the anterior neck region, not ascribable to malignancy, confirmed with (99m)Tc-sestamibi scintigraphy. It was removed by minimally invasive surgery. It was shown to be an oxyphil parathyroid adenoma localized in an unusual site.

Keywords: (18)F-FDG PET/CT; (18)F-FDG PET/TC; Adenoma de paratiroides; Hipercalcemia; Hodgkin's Lymphoma; Hypercalcemia; Linfoma de Hodgkin; Oxifílico; Oxyphil; Parathyroid adenoma.

Publication types

  • Case Reports

MeSH terms

  • Adenoma, Oxyphilic / complications
  • Adenoma, Oxyphilic / diagnostic imaging*
  • Adult
  • Choristoma / diagnostic imaging
  • Fluorine Radioisotopes / analysis*
  • Fluorodeoxyglucose F18 / analysis*
  • Hodgkin Disease / blood*
  • Humans
  • Hypercalcemia / etiology
  • Hyperparathyroidism, Primary / complications
  • Hyperparathyroidism, Primary / diagnostic imaging*
  • Male
  • Neck
  • Neoplasms, Multiple Primary / diagnostic imaging*
  • Paraneoplastic Syndromes / etiology
  • Parathyroid Glands / diagnostic imaging
  • Parathyroid Neoplasms / complications
  • Parathyroid Neoplasms / diagnostic imaging*
  • Positron Emission Tomography Computed Tomography*
  • Radiopharmaceuticals / analysis*
  • Technetium Tc 99m Sestamibi / analysis

Substances

  • Fluorine Radioisotopes
  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18
  • Technetium Tc 99m Sestamibi

Supplementary concepts

  • Humoral Hypercalcemia Of Malignancy