Aggressive fibromatosis: evaluation of prognostic factors and outcomes of surgical treatment

Acta Orthop Traumatol Turc. 2014;48(1):55-60. doi: 10.3944/AOTT.2014.3171.

Abstract

Objective: The aim of this study was to evaluate the results of surgical treatment of aggressive fibromatosis and the effects of prognostic factors on recurrence.

Methods: Forty patients (24 female, 16 male; average age: 31.2 years) diagnosed with aggressive fibromatosis were evaluated retrospectively. Nine patients with tumor-positive surgical margins macroscopically were excluded. Prognostic factors such as age, gender, localization, admission status, compartment status, surgical margin, tumor size and adjuvant radiotherapy were evaluated.

Results: Recurrence rate was 29%. Average disease free survival was 46±4 months. There was no statistically significant relation between prognostic factors and recurrence. Clinical results of the patients receiving adjuvant radiotherapy were more satisfactory.

Conclusion: Adjuvant radiotherapy administration appears to be a rational treatment method instead of sacrificing function to achieve wide surgical margins.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Child, Preschool
  • Desmoid Tumors / surgery*
  • Disease-Free Survival
  • Female
  • Humans
  • Limb Salvage
  • Male
  • Middle Aged
  • Prognosis
  • Radiotherapy Dosage
  • Radiotherapy, Adjuvant
  • Recurrence
  • Treatment Outcome
  • Young Adult