RAS-associated lymphoproliferative disease evolves into severe juvenile myelo-monocytic leukemia

Blood. 2014 Mar 20;123(12):1960-3. doi: 10.1182/blood-2014-01-548958.

Authors

Nina Lanzarotti¹, Julie Bruneau, Amélie Trinquand, Marie-Claude Stolzenberg, Bénédicte Neven, Julien Fregeac, Eva Levy, Nadia Jeremiah, Felipe Suarez, Nizar Mahlaoui, Alain Fischer, Aude Magerus-Chatinet, Hélène Cavé, Frédéric Rieux-Laucat

Affiliation

¹ INSERM UMR 1163, Laboratory of Immunogenetics of Pediatric Autoimmune Diseases, Paris, France Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Paris, France.

PMID: 24652966
DOI: 10.1182/blood-2014-01-548958

No abstract available

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Age Factors
Bone Marrow / pathology
Child
Child, Preschool
Genes, ras*
Humans
Leukemia, Myelomonocytic, Juvenile / etiology
Leukemia, Myelomonocytic, Juvenile / genetics*
Leukemia, Myelomonocytic, Juvenile / pathology
Lymphoproliferative Disorders / etiology
Lymphoproliferative Disorders / genetics*
Lymphoproliferative Disorders / pathology
Male
Mutation
Spleen / pathology
Young Adult