Phage-based detection of bacterial pathogens

Analyst. 2014 Jun 7;139(11):2617-26. doi: 10.1039/c4an00208c.

Abstract

Bacterial pathogens cause significant morbidity and mortality annually to both humans and animals. With the rampant spread of drug resistance and the diminishing effectiveness of current antibiotics, there is a pressing need for effective diagnostics for detection of bacterial pathogens and their drug resistances. Bacteriophages offer several unique opportunities for bacterial detection. This review highlights the means by which bacteriophages have been utilized to achieve and facilitate specific bacterial detection.

Publication types

  • Review

MeSH terms

  • Bacteria / drug effects
  • Bacteria / isolation & purification*
  • Bacteriophages / physiology*
  • Drug Resistance, Microbial