Cerebrospinal fluid levels of beta-endorphin in patients with fibromyalgia (fibrositis syndrome)

H Vaeroy; R Helle; O Førre; E Kåss; L Terenius

Cerebrospinal fluid levels of beta-endorphin in patients with fibromyalgia (fibrositis syndrome)

J Rheumatol. 1988 Dec;15(12):1804-6.

Authors

H Vaeroy¹, R Helle, O Førre, E Kåss, L Terenius

Affiliation

¹ Department of Rheumatology Oslo Sanitetsforenings Rheumatism Hospital, Norway.

PMID: 2466120

Abstract

Cerebrospinal fluid (CSF) samples from 18 female patients with fibromyalgia (fibrositis syndrome) were analyzed for beta-endorphin. The mean CSF level of beta-endorphin was 20.7 +/- 0.7 fmol/ml in the patients compared to 20.5 +/- 2.0 fmol/ml (mean +/- SEM) in healthy controls (p greater than 0.05). Thus, patients with fibromyalgia (fibrositis syndrome) seem to have normal CSF levels of the pain modulatory neuropeptide beta-endorphin.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Female
Fibromyalgia / cerebrospinal fluid*
Humans
Middle Aged
Radioimmunoassay
Substance P / cerebrospinal fluid
beta-Endorphin / cerebrospinal fluid*

Substances

Substance P
beta-Endorphin