[Importance of FDG-PET/CT for surgery of rectal cancer]

Chirurg. 2014 Jun;85(6):487-92. doi: 10.1007/s00104-013-2669-7.
[Article in German]

Abstract

Background: Examinations using 18F-fluorodeoxyglucose positron emission tomography-computed tomography (FDG-PET/CT) are becoming increasingly more important in clinical practice for the diagnosis and therapy of cancer patients.

Question: What role does FDG-PET/CT examination play in the diagnosis and therapy of rectal cancer?

Results: The FDG-PET/CT method is especially valuable during postoperative care when a recurrence is suspected. Especially when tumor marker levels rise with no other symptoms, FDG-PET/CT can be used to evaluate unclear lesions in the liver and unclear tissue formations at the surgery site and distinguish between scar tissue and recurring tumors. Currently, there is increasing evidence that a survival prognosis may be possible based on the tracer uptake of FDG-PET/CT. There is also a great interest in the possibility of evaluating the success of neoadjuvant therapy with FDG-PET/CT.

Discussion: Despite some limitations FDG-PET/CT plays a significant role in the diagnosis and treatment of patients with rectal cancer.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Diagnosis, Differential
  • Disease Progression
  • Fluorodeoxyglucose F18*
  • Follow-Up Studies
  • Humans
  • Molecular Imaging / methods*
  • Multimodal Imaging / methods*
  • Neoplasm Recurrence, Local / diagnosis
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Recurrence, Local / surgery
  • Neoplasm Staging
  • Positron-Emission Tomography / methods*
  • Rectal Neoplasms / diagnosis*
  • Rectal Neoplasms / pathology
  • Rectal Neoplasms / surgery*
  • Rectum / pathology
  • Rectum / surgery
  • Sensitivity and Specificity
  • Tomography, X-Ray Computed / methods*

Substances

  • Fluorodeoxyglucose F18