Haploidentical stem cell transplantation in DOCK8 deficiency - Successful control of pre-existing severe viremia with a TCRaß/CD19-depleted graft and antiviral treatment

Clin Immunol. 2014 May-Jun;152(1-2):111-4. doi: 10.1016/j.clim.2014.03.006. Epub 2014 Mar 22.
No abstract available

Keywords: DOCK8 deficiency; HSCT; Hyper IgE; Primary immunodeficiency.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adolescent
  • Antigens, CD19 / immunology
  • Antiviral Agents / therapeutic use*
  • BK Virus
  • Female
  • Guanine Nucleotide Exchange Factors / genetics
  • Hematopoietic Stem Cell Transplantation / methods*
  • Humans
  • Immunoglobulin G / therapeutic use
  • Job Syndrome / complications
  • Job Syndrome / genetics
  • Job Syndrome / surgery*
  • Lymphocyte Depletion
  • Polyomavirus Infections / complications
  • Polyomavirus Infections / drug therapy*
  • Receptors, Antigen, T-Cell, alpha-beta / immunology
  • T-Lymphocytes / immunology
  • Tumor Virus Infections / complications
  • Tumor Virus Infections / drug therapy*
  • Turkey
  • Viremia / complications
  • Viremia / drug therapy*

Substances

  • Antigens, CD19
  • Antiviral Agents
  • DOCK8 protein, human
  • Guanine Nucleotide Exchange Factors
  • Immunoglobulin G
  • Receptors, Antigen, T-Cell, alpha-beta