Gross pathology and endocrinology of ovarian cysts in bitches

Reprod Domest Anim. 2014 Jun;49(3):463-8. doi: 10.1111/rda.12311. Epub 2014 Apr 4.

Abstract

A total of 73 bitches with ovarian cysts were ovariohysterectomized. Cysts were characterized by gross pathology and endocrine parameters. Therefore, oestradiol-17ß and progesterone concentrations were assessed in cyst-fluid and corresponding blood plasma in each bitch. Our data demonstrated that multiple cysts were often present in a single individual (82%) and that cysts were commonly found on both ovaries (77%). The number of cysts per individual varied from 1 to 35. Most cysts were small in size (range 0.2-4.0 cm in diameter). No cyst was found to produce solely oestradiol-17ß or progesterone. Plasma levels of oestradiol-17ß and progesterone for a given individual were positively correlated with levels of these same hormones in their cyst-fluid (r = 0.334 and p = 0.001 for oestradiol-17ß; r = 0.419 and p < 0.001 for progesterone). Our study is the first to provide a comprehensive evaluation of the gross pathology and endocrinology of ovarian cysts in a larger number of bitches.

MeSH terms

  • Animals
  • Dog Diseases / metabolism*
  • Dog Diseases / pathology*
  • Dogs
  • Estradiol / analysis
  • Estradiol / blood
  • Female
  • Ovarian Cysts / metabolism
  • Ovarian Cysts / pathology
  • Ovarian Cysts / veterinary*
  • Progesterone / analysis
  • Progesterone / blood

Substances

  • Progesterone
  • Estradiol