Synthesis and optical properties of water-soluble biperylene-based dendrimers

Chem Commun (Camb). 2014 May 30;50(42):5648-51. doi: 10.1039/c4cc01742k.

Abstract

We report the synthesis and photophysical properties of three biperylene-based dendrimers, which show red fluorescence in water. A fluorescence microscopy study demonstrated uptake of biperylene-based dendrimers in living cells. Our results indicate that these biperylene-based dendrimers are promising candidates in fluorescence imaging applications with the potential as therapeutic carriers.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line, Tumor
  • Chemistry Techniques, Synthetic
  • Dendrimers / chemical synthesis*
  • Dendrimers / chemistry*
  • Drug Carriers / chemical synthesis*
  • Drug Carriers / chemistry*
  • Humans
  • Microscopy, Fluorescence
  • Optical Phenomena*
  • Perylene / chemistry*
  • Solubility
  • Water / chemistry*

Substances

  • Dendrimers
  • Drug Carriers
  • Water
  • Perylene