Cancer phenotypic lethality, exemplified by the non-essential MTH1 enzyme being required for cancer survival

Ann Oncol. 2014 Jul;25(7):1253-1255. doi: 10.1093/annonc/mdu158. Epub 2014 Apr 15.
No abstract available

Publication types

  • Editorial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Survival*
  • DNA Repair Enzymes / genetics*
  • Humans
  • Neoplasms* / enzymology
  • Neoplasms* / pathology
  • Neoplasms* / therapy
  • Phenotype
  • Phosphoric Monoester Hydrolases / genetics*

Substances

  • Phosphoric Monoester Hydrolases
  • 8-oxodGTPase
  • DNA Repair Enzymes