Eruptive cutaneous squamous cell carcinoma and psoriasis: response to cetuximab

Clin Exp Dermatol. 2014 Jul;39(5):604-7. doi: 10.1111/ced.12341. Epub 2014 Apr 23.

Abstract

Cutaneous squamous cell carcinomas (CSCCs) comprise 20-30% of nonmelanoma skin cancers (NMSCs), and continue to increase in incidence. We report a case of a patient with severe psoriasis who had recurrent and eruptive CSCCs on her leg, which were successfully treated with cetuximab and radiotherapy. The patient had successful long-term clearance of her skin tumours, with the additional finding of resolution of psoriasis while on cetuximab therapy.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Antibodies, Monoclonal, Humanized / therapeutic use*
  • Antineoplastic Agents / therapeutic use*
  • Carcinoma, Squamous Cell / drug therapy*
  • Cetuximab
  • Combined Modality Therapy / methods
  • Female
  • Humans
  • Leg
  • Psoriasis / drug therapy*
  • Skin Neoplasms / drug therapy*
  • Treatment Outcome

Substances

  • Antibodies, Monoclonal, Humanized
  • Antineoplastic Agents
  • Cetuximab