Serum levels of trace elements in patients with prostate cancer

Asian Pac J Cancer Prev. 2014;15(6):2625-9. doi: 10.7314/apjcp.2014.15.6.2625.

Abstract

Background: Trace elements are major components of biological structures; however, excessive levels of these elements can be toxic.

Materials and methods: In the present study, serum levels of trace elements were measured in 30 patients with newly diagnosed as prostate cancer and 32 healthy volunteer by using furnace atomic absorption spectrophotometry.

Results: It was found that there was an increase in serum levels of Co, Cu, Mg and Pb (p<0.05), whereas a decrease in serum levels of Fe, Mn, and Zn levels in patients with prostate cancer (p<0.05).

Conclusions: These changes may be important in the pathogenesis of prostate cancers; however, further prospective studies are needed to identify relationships between prostate cancer and trace elements.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Biomarkers, Tumor / blood*
  • Case-Control Studies
  • Humans
  • Male
  • Prognosis
  • Prostate / metabolism*
  • Prostatic Neoplasms / blood*
  • Prostatic Neoplasms / diagnosis
  • Spectrophotometry, Atomic
  • Trace Elements / blood*

Substances

  • Biomarkers, Tumor
  • Trace Elements