PET-CT scanner characterization for PET raw data use in biomedical research

Chiara Gianoli; Marco Riboldi; Christopher Kurz; Elisabetta De Bernardi; Julia Bauer; Giulia Fontana; Mario Ciocca; Katia Parodi; Guido Baroni

doi:10.1016/j.compmedimag.2014.03.008

PET-CT scanner characterization for PET raw data use in biomedical research

Comput Med Imaging Graph. 2014 Jul;38(5):358-68. doi: 10.1016/j.compmedimag.2014.03.008. Epub 2014 Apr 4.

Authors

Chiara Gianoli¹, Marco Riboldi², Christopher Kurz³, Elisabetta De Bernardi⁴, Julia Bauer⁵, Giulia Fontana⁶, Mario Ciocca⁷, Katia Parodi⁸, Guido Baroni⁹

Affiliations

¹ Heidelberg Ion Beam Therapy Center and Department of Radiation Oncology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Dipartimento di Elettronica, Informazione e Bioingegneria (DEIB), Politecnico di Milano, P.za Leonardo da Vinci 32, 20133 Milano, Italy. Electronic address: [email protected].
² Dipartimento di Elettronica, Informazione e Bioingegneria (DEIB), Politecnico di Milano, P.za Leonardo da Vinci 32, 20133 Milano, Italy. Electronic address: [email protected].
³ Heidelberg Ion Beam Therapy Center and Department of Radiation Oncology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany. Electronic address: [email protected].
⁴ Department of Health Sciences - Tecnomed Foundation, University of Milano-Bicocca, via Cadore 48, 20090 Monza, Italy. Electronic address: [email protected].
⁵ Heidelberg Ion Beam Therapy Center and Department of Radiation Oncology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany. Electronic address: [email protected].
⁶ Unità di Bioingegneria Clinica, Strada Privata Campeggi, 53, 27100 Pavia, Italy. Electronic address: [email protected].
⁷ Unità di Fisica Medica, Strada Privata Campeggi, 53, 27100 Pavia, Italy. Electronic address: [email protected].
⁸ Heidelberg Ion Beam Therapy Center and Department of Radiation Oncology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Ludwig Maximilians University (LMU) Munich, Experimental Physics - Medical Physics, Am Coulombwall 1, 85748 Garching, Germany. Electronic address: [email protected].
⁹ Dipartimento di Elettronica, Informazione e Bioingegneria (DEIB), Politecnico di Milano, P.za Leonardo da Vinci 32, 20133 Milano, Italy. Electronic address: [email protected].

PMID: 24766905
DOI: 10.1016/j.compmedimag.2014.03.008

Abstract

The purpose of this paper is to describe the experiments and methods that led to the geometrical interpretation of new-generation commercial PET-CT scanners, finalized to off-line PET-based treatment verification in ion beam therapy. Typically, the geometrical correspondence between the image domain (i.e., the dicom PET) and the sinogram domain (i.e., the PET raw data) is not explicitly described by scanner vendors. Hence, the proposed characterization can be applied to commercial PET-CT scanners used in biomedical research, for the development of technologies and methods requiring the use of PET raw data, without having access to confidential information from the vendors.

Keywords: Biomedical imaging; Data interpretation; PET imaging; PET raw data; dicom PET image.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Algorithms
Biomedical Research*
Humans
Image Interpretation, Computer-Assisted*
Positron-Emission Tomography / instrumentation*