[The threat of the carbapenemase-producing enterobacteriaceae in Spain: positioning report of the SEIMC study groups, GEIH and GEMARA]

Enferm Infecc Microbiol Clin. 2014 Dec;32(10):666-70. doi: 10.1016/j.eimc.2014.02.011. Epub 2014 Apr 22.
[Article in Spanish]

Abstract

The emergence and spread of carbapenemase-producing Enterobacteriaceae (CPE), as the current paradigm of extensive drug-resistance and multi-drug resistance to antibiotics, is a serious threat to patient health and public health. The increase in OXA-48- and VIM-1-producing Klebsiella pneumoniae isolates represents the greatest impact of CPE in Spain. This evidence has lead the members of a representative panel of the Spanish Study Groups of Nosocomial Infections and Mechanisms of Action and Resistance to Antimicrobials of the Spanish Society of Clinical Microbiology and Infectious Diseases (GEIH/GEMARA-SEIMC) to make a position statement expressing the need for: (i) definitive and coordinated action by all health professionals and authorities involved, and (ii) an adaptation of health systems to facilitate their early control and minimize their impact.

Keywords: Carbapenemasas; Carbapenemases; Enterobacteriaceae; Enterobacterias; Extensive drug-resistance; Resistencia extensa a antibióticos.

MeSH terms

  • Bacterial Proteins / biosynthesis*
  • Drug Resistance, Bacterial*
  • Enterobacteriaceae / drug effects
  • Enterobacteriaceae / enzymology*
  • Enterobacteriaceae Infections / drug therapy
  • Enterobacteriaceae Infections / prevention & control
  • Humans
  • Spain
  • beta-Lactamases / biosynthesis*

Substances

  • Bacterial Proteins
  • beta-Lactamases
  • carbapenemase