Distinct roles of class I PI3K isoforms in multiple myeloma cell survival and dissemination

Blood Cancer J. 2014 Apr 25;4(4):e204. doi: 10.1038/bcj.2014.24.

Authors

I Sahin¹, M Moschetta¹, Y Mishima¹, S V Glavey¹, B Tsang¹, F Azab², S Manier¹, Y Zhang¹, P Maiso¹, A Sacco¹, A K Azab², A M Roccaro¹, I M Ghobrial¹

Affiliations

¹ Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
² 1] Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA [2] Cancer Biology Division, Department of Radiation Oncology, School of Medicine, Washington University in St Louis, St Louis, MO, USA.

No abstract available

Publication types

Letter

MeSH terms

Animals
Cell Survival
Disease Progression
Gene Knockdown Techniques
Humans
Isoenzymes
Mice
Mice, SCID
Multiple Myeloma / enzymology*
Multiple Myeloma / pathology
Phosphatidylinositol 3-Kinases / metabolism*
Proto-Oncogene Proteins c-akt / metabolism

Substances

Isoenzymes
Phosphatidylinositol 3-Kinases
Proto-Oncogene Proteins c-akt

Grants and funding

R01 CA154648/CA/NCI NIH HHS/United States