Abstract
Correlation between level of ALDH1 expression and metastases development in patients with colorectal adenocarcinoma was not revealed. Proliferation of stem cancer cells (ALDH1-positive) was significantly lower comparatively ALDH-1 negative tumor cells (p < 0.001). Proliferation of stem cancer cells vary from 0,1% to 10%.
MeSH terms
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Adenocarcinoma / metabolism
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Adenocarcinoma / pathology*
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Aldehyde Dehydrogenase 1 Family
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Cell Proliferation*
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Colorectal Neoplasms / metabolism
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Colorectal Neoplasms / pathology*
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Humans
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Isoenzymes / metabolism*
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Ki-67 Antigen / metabolism
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Neoplastic Stem Cells / metabolism
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Neoplastic Stem Cells / pathology*
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Retinal Dehydrogenase / metabolism*
Substances
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Isoenzymes
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Ki-67 Antigen
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Aldehyde Dehydrogenase 1 Family
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ALDH1A1 protein, human
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Retinal Dehydrogenase