Modified liver mobilization for the treatment of renal cell carcinoma with thrombosis involving the intrahepatic inferior vena cava

World J Surg Oncol. 2014 Apr 29:12:131. doi: 10.1186/1477-7819-12-131.

Abstract

Background: We aimed to evaluate the feasibility and clinical significance of using a modified liver-mobilization technique to treat renal cell carcinoma (RCC) combined with intrahepatic inferior vena cava (IVC) thrombosis.

Methods: A total of 11 level III thrombus patients underwent radical nephrectomy with resection of the tumor thrombus from intrahepatic IVC. A father clamp was used in combination with hepatic portal blocking to control the IVC.

Results: The intraoperative mortality and postoperative complications were reduced in 11 cases of RCC with intrahepatic IVC thrombosis. The mean blood loss was 800 mL, and mean patient hospital stay was 13 days. Follow-up was conducted for one to four months, with only two cases of recurrence recorded.

Conclusions: The proposed modified liver-mobilization technique could safely and effectively treat RCC and reduce intrahepatic IVC thrombosis.

MeSH terms

  • Adult
  • Aged
  • Carcinoma, Renal Cell / complications
  • Carcinoma, Renal Cell / mortality
  • Carcinoma, Renal Cell / surgery*
  • Feasibility Studies
  • Female
  • Follow-Up Studies
  • Humans
  • Kidney Neoplasms / complications
  • Kidney Neoplasms / mortality
  • Kidney Neoplasms / surgery*
  • Liver / pathology
  • Liver / surgery*
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Neoplastic Cells, Circulating
  • Nephrectomy / methods*
  • Postoperative Complications / mortality
  • Postoperative Complications / prevention & control*
  • Prognosis
  • Survival Rate
  • Thrombectomy / methods*
  • Thrombosis / complications
  • Thrombosis / mortality
  • Thrombosis / surgery*
  • Vena Cava, Inferior / pathology
  • Vena Cava, Inferior / surgery*