Invasive treatment of non-ST-segment elevation acute coronary syndrome: cardiac catheterization/revascularization for all?

Rev Esp Cardiol (Engl Ed). 2014 Mar;67(3):218-21. doi: 10.1016/j.rec.2013.11.004. Epub 2014 Jan 31.

Abstract

Patients admitted to hospital with symptoms and signs of non-ST-segment elevation acute coronary syndromes have different risk profiles and are in need of an individualized approach that takes into consideration not only age and sex but also comorbidities such as diabetes, renal failure, hypertension, heart failure, peripheral artery disease, earlier revascularization, etc. According to evidence-based medicine and as documented in current guidelines, there is currently evidence for early catheterization and, if feasible, revascularization in high-risk patients, especially in men. Nevertheless, because of a lack of definitive evidence, there is uncertainty about treating women in the same way. Because women are usually older and have more comorbidities, they are frailer and revascularization should be indicated with greater caution. There is no evidence that catheterization as such is worse for women than for men; however, for both men and women with low risk, a less invasive approach, such as coronary computed tomography angiography, could be considered as a first diagnostic tool.

Keywords: Estratificación del riesgo; Invasive treatment; Non–ST-segment elevation acute coronary syndrome; Risk stratification; Síndrome coronario agudo sin elevación del segmento ST; Tratamiento invasivo.

MeSH terms

  • Acute Coronary Syndrome / therapy*
  • Cardiac Catheterization*
  • Coronary Angiography
  • Female
  • Humans
  • Male
  • Myocardial Revascularization*
  • Patient Selection
  • Risk Assessment
  • Sex Factors