Sparsity-regularized image reconstruction of decomposed K-edge data in spectral CT

Phys Med Biol. 2014 May 21;59(10):N65-79. doi: 10.1088/0031-9155/59/10/N65. Epub 2014 Apr 28.

Abstract

The development of spectral computed tomography (CT) using binned photon-counting detectors has garnered great interest in recent years and has enabled selective imaging of K-edge materials. A practical challenge in CT image reconstruction of K-edge materials is the mitigation of image artifacts that arise from reduced-view and/or noisy decomposed sinogram data. In this note, we describe and investigate sparsity-regularized penalized weighted least squares-based image reconstruction algorithms for reconstructing K-edge images from few-view decomposed K-edge sinogram data. To exploit the inherent sparseness of typical K-edge images, we investigate use of a total variation (TV) penalty and a weighted sum of a TV penalty and an ℓ1-norm with a wavelet sparsifying transform. Computer-simulation and experimental phantom studies are conducted to quantitatively demonstrate the effectiveness of the proposed reconstruction algorithms.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Computer Simulation
  • Humans
  • Image Processing, Computer-Assisted / methods*
  • Metal Nanoparticles
  • Phantoms, Imaging
  • Tomography, X-Ray Computed / methods*
  • Ytterbium

Substances

  • Ytterbium