Abstract
Six novel acyclic sulfides, named garlicnins L-1-L-4 (1-4), E (5), and F (6), were isolated from the acetone extracts, with the ability to suppress M2 macrophage activation, of the bulbs of garlic (Allium sativum L.), and their chemical structures were characterized.
MeSH terms
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Garlic / chemistry*
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Humans
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Macrophages / drug effects*
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Molecular Structure
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Structure-Activity Relationship
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Sulfides / chemistry
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Sulfides / isolation & purification
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Sulfides / pharmacology*
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Thiophenes / chemistry
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Thiophenes / isolation & purification
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Thiophenes / pharmacology*