Quantitative computer tomography analysis of post-operative subdural fluid volume predicts recurrence of chronic subdural haematoma

Brain Inj. 2014;28(8):1121-6. doi: 10.3109/02699052.2014.910702. Epub 2014 May 6.

Abstract

Background: Post-operative volume of subdural fluid is considered to correlate with recurrence in chronic subdural haematoma (CSDH). Information on the applications of computer-assisted volumetric analysis in patients with CSDHs is lacking.

Objective: To investigate the relationship between haematoma recurrence and longitudinal changes in subdural fluid volume using CT volumetric analysis.

Methods: Fifty-four patients harbouring 64 CSDHs were studied prospectively. The association between recurrence rate and CT findings were investigated.

Results: Eleven patients (20.4%) experienced post-operative recurrence. Higher pre-operative (over 120 ml) and/or pre-discharge subdural fluid volumes (over 22 ml) were significantly associated with recurrence; the probability of non-recurrence for values below these thresholds were 92.7% and 95.2%, respectively. CSDHs with larger pre-operative (over 15.1 mm) and/or residual (over 11.7 mm) widths also had significantly increased recurrence rates. Bilateral CSDHs were not found to be more likely to recur in this series. On receiver-operating characteristic curve, the areas under curve for the magnitude of changes in subdural fluid volume were greater than a single time-point measure of either width or volume of the subdural fluid cavity.

Conclusions: Close imaging follow-up is important for CSDH patients for recurrence prediction. Using quantitative CT volumetric analysis, strong evidence was provided that changes in the residual fluid volume during the 'self-resolution' period can be used as significantly radiological predictors of recurrence.

Keywords: Chronic subdural haematoma; computer tomography; computer-assisted volumetric analysis; outcome; recurrence.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Decompressive Craniectomy*
  • Female
  • Follow-Up Studies
  • Hematoma, Subdural, Chronic / diagnostic imaging*
  • Hematoma, Subdural, Chronic / pathology*
  • Hematoma, Subdural, Chronic / prevention & control
  • Humans
  • Male
  • Middle Aged
  • Pilot Projects
  • Postoperative Period
  • Predictive Value of Tests
  • Prospective Studies
  • Recurrence
  • Risk Assessment
  • Subdural Space / diagnostic imaging
  • Subdural Space / pathology
  • Tomography, X-Ray Computed*