[Tako-tsubo syndrome: analysis of a series of 60 cases]

Med Clin (Barc). 2014 Sep 15;143(6):255-60. doi: 10.1016/j.medcli.2014.02.027. Epub 2014 May 10.
[Article in Spanish]

Abstract

Background and objective: The Tako-tsubo syndrome (TS) is a reversible acute cardiomyopathy simulating an infarction. We analyzed 60 patients admitted with TS in our center.

Patients and method: A percentage of 73.3 were women (mean age: 70.6 ± 11.8 years); 83.3% had some cardiovascular risk factor, 25% had an anxiety-depressive disorder and in 58.3% a precipitating factor was identified, emotional stress being the most frequent. A percentage of 15.3 showed complete left bundle branch block (LBBB). In 23.3% of patients, contractile abnormalities respected the apex (mid ventricular or diaphragmatic types).

Results: The anterior descending artery showed no significant lesions in 35% of patients and in 68.3% it had a diaphragmatic segment. Forty percent of patients developed heart failure (HF) and 18.3% cardiogenic shock (CS). The overall in-hospital mortality was 3.3%, while it was 8.3% among those patients who developed HF. The incidence of CS was higher among patients with LBBB (44.4 vs. 13.7%, P=.05) and males (43.8 vs. 9.1%, P=.005).

Conclusions: Although in-hospital mortality in patients admitted due to TS is low, a significant percentage of these patients develop HF with a high mortality in this subgroup. Males and patients with LBBB had higher in-hospital morbidity.

Keywords: Discinesia apical transitoria; Heart failure; Insuficiencia cardiaca; Síndrome de Tako-tsubo; Tako-tsubo syndrome; Transient apical ballooning syndrome.

Publication types

  • English Abstract

MeSH terms

  • Acute Coronary Syndrome / etiology
  • Adult
  • Age Distribution
  • Aged
  • Anxiety Disorders / complications
  • Bundle-Branch Block / epidemiology
  • Depressive Disorder / complications
  • Female
  • Heart Failure / epidemiology
  • Heart Failure / etiology
  • Hospital Mortality
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Postoperative Complications / epidemiology
  • Retrospective Studies
  • Risk Factors
  • Sex Distribution
  • Shock, Cardiogenic / etiology
  • Spain / epidemiology
  • Stress, Psychological / complications
  • Takotsubo Cardiomyopathy / complications
  • Takotsubo Cardiomyopathy / diagnosis
  • Takotsubo Cardiomyopathy / epidemiology*