Facial abnormalities in Nablus mask-like facial syndrome: multidetector computed tomography findings

J Oral Maxillofac Surg. 2014 Aug;72(8):1579-84. doi: 10.1016/j.joms.2014.01.013. Epub 2014 Jan 23.

Abstract

Nablus mask-like facial syndrome (NMLFS) is a rare microdeletion syndrome characterized by a mask-like facial appearance. NMLFS has been reported in only 6 patients and has a recognizable facial appearance, along with other clinical features. The first case of NMLFS has been described by Teebi in 2000, in a 4-year-old Palestinian boy. Three years later, Salpietro et al reported a second example of NMLFS in a 21-month-old girl. The same patient recently came to our hospital to undergo a computed tomography (CT) study to evaluate the degree of development of the zygomatic-maxillary region for orthodontic treatment and orthognathic surgery. To the best of our knowledge, no reports have previously illustrated the maxillofacial CT findings of NMLFS in the radiologic data. We report the multidetector CT (MDCT) facial characteristics/abnormalities of this syndrome, emphasizing the usefulness of multiplanar reformations (MPRs) in preoperative planning.

Publication types

  • Case Reports

MeSH terms

  • Abnormalities, Multiple / diagnostic imaging*
  • Abnormalities, Multiple / physiopathology
  • Abnormalities, Multiple / surgery
  • Blepharophimosis / diagnostic imaging*
  • Blepharophimosis / physiopathology
  • Blepharophimosis / surgery
  • Child
  • Craniofacial Abnormalities / diagnostic imaging*
  • Craniofacial Abnormalities / physiopathology
  • Craniofacial Abnormalities / surgery
  • Face / abnormalities*
  • Female
  • Humans
  • Tomography, X-Ray Computed / methods*

Supplementary concepts

  • Nablus mask-like facial syndrome